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A 2019 systematic review published in the National Library of Medicine identified improvements in skin brightness across several small trials while emphasising the need for larger controlled studies before definitive claims can be made

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AOD-9604 is the more-studied stabilized version Compound Human Growth Hormone (somatropin) Class Full-length recombinant hGH FDA Status FDA-approved for specific indications (GH deficiency, certain growth disorders, AIDS wasting) Evidence Strength Strong human evidence for approved indications

Access still varies by indication, insurance policy, prior authorization rules and the availability of covered alternatives